A chalazion is most closely associated with obstruction of which glands?

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Study for the NBEO Ocular Disease Part 1 Test. Use flashcards and multiple choice questions, each with hints and explanations, to prepare for your exam! Get ready for your success!

Multiple Choice

A chalazion is most closely associated with obstruction of which glands?

Explanation:
Chalazion arises when the lipid-secreting Meibomian glands in the eyelid become obstructed. These glands (in the tarsal plates) produce the oily component of the tear film. When a duct is blocked, secretions accumulate and trigger a chronic granulomatous inflammatory reaction, forming a painless, firm nodule inside the eyelid. This contrasts with infections of glands at the lash margin (Glands of Zeiss and Moll) that cause external styes, and with lacrimal gland issues that affect tear production rather than producing a lid lump. So obstruction of the Meibomian glands best explains a chalazion.

Chalazion arises when the lipid-secreting Meibomian glands in the eyelid become obstructed. These glands (in the tarsal plates) produce the oily component of the tear film. When a duct is blocked, secretions accumulate and trigger a chronic granulomatous inflammatory reaction, forming a painless, firm nodule inside the eyelid. This contrasts with infections of glands at the lash margin (Glands of Zeiss and Moll) that cause external styes, and with lacrimal gland issues that affect tear production rather than producing a lid lump. So obstruction of the Meibomian glands best explains a chalazion.

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