An external hordeolum primarily affects which glands?

• A. Glands of Zeiss and Moll
• B. Meibomian glands
• C. Glands of Wolfring
• D. Lacrimal gland

Answer: (A)

External hordeolum is a superficial eyelid infection at the lash margin, involving the glands that open there—the glands of Zeis and Moll. The Zeis glands are sebaceous glands attached to each eyelash, and the Moll glands are small apocrine sweat glands nearby. Infection of these margin glands produces a tender, red nodule at the lash line, often with purulent discharge. In contrast, the meibomian glands inside the eyelid (in the tarsal plate) cause an internal hordeolum when infected, presenting as a painful lump within the eyelid rather than at the margin. The lacrimal gland is responsible for tear production and its involvement leads to tearing or lacrimation issues rather than a stye at the eyelid margin. Wolfring glands are deeper accessory meibomian glands and are not the typical site for an external hordeolum. So the glands primarily affected are the glands of Zeis and Moll.