Dalrymple's sign is described as lid retraction with a stare in thyroid eye disease. Which option lists this sign?

• A. Von Graefe's sign
• B. Kocher's sign
• C. Dalrymple's sign
• D. Stellwag's sign

Answer: (C)

Lid retraction with a staring appearance is a hallmark of Graves' ophthalmopathy, reflecting overactivity and fibrosis of the eyelid muscles that keep the lid pulled up. This specific sign, named for its descriptor of the raised upper lid and prominent scleral exposure, is Dalrymple's sign. Recognizing this helps distinguish lid position abnormalities seen in thyroid eye disease from other eyelid signs: Stellwag's sign is infrequent blinking, Von Graefe's sign involves a lag of the upper lid on downward gaze, and Kocher's sign denotes a different eyelid finding not describing the lid retraction with scleral show. Therefore, the described lid retraction with a stare fits Dalrymple's sign.