Interstitial keratitis is part of which congenital infection's triad?

• A. Congenital rubella
• B. Congenital syphilis
• C. Toxoplasmosis
• D. CMV

Answer: (B)

Interstitial keratitis is a classic ocular finding in congenital syphilis and is part of the Hutchinson triad, which includes interstitial keratitis, Hutchinson teeth, and eighth-nerve (sensorineural) deafness. The corneal involvement results from syphilitic inflammation of the corneal stroma, often developing after birth, and it serves as a distinguishing feature of congenital syphilis compared with other congenital infections. Rubella is associated with cataracts, patent ductus arteriosus, and deafness; toxoplasmosis with chorioretinitis, hydrocephalus, and intracranial calcifications; CMV can cause chorioretinitis among other findings but does not form this specific triad.