Ocular Rosacea primarily targets sebaceous glands. Which statement best describes the glands involved?

• A. Meibomian glands and Glands of Zeiss are involved
• B. Meibomian glands are involved
• C. Glands of Zeiss are involved
• D. Lacrimal gland is involved

Answer: (A)

Ocular rosacea tends to affect the sebaceous units of the eyelids. The Meibomian glands, located in the inside of the eyelids, secrete the lipid layer that helps prevent tear evaporation, and inflammation or blockage of these glands (meibomian gland dysfunction) is a clear hallmark. The Glands of Zeiss are tiny sebaceous glands at the base of the eyelashes and can also become inflamed in rosacea, contributing to lid-margin irritation and blepharitis. The lacrimal gland, by contrast, produces the watery component of tears and is not a sebaceous gland, so it is not the primary target in ocular rosacea. Thus, both the Meibomian glands and the Glands of Zeiss being involved best describes the glands affected.