Which of the following is NOT true regarding Thygeson's Superficial Punctate Keratopathy?

• A. It is almost always unilateral
• B. Foreign body sensation is the major symptom
• C. It presents with superficial, intraepithelial, raised central corneal lesions
• D. It is characterized by acute phases and remissions

Answer: (A)

Thygeson's keratopathy is a chronic, usually bilateral superficial epithelial keratopathy with recurrent episodes. The key point is that it is not almost always unilateral; most patients have involvement in both eyes or eye involvement that alternates over time, so claiming it’s almost always one eye is incorrect. Patients typically report foreign body sensation as a prominent symptom, and the corneal findings are superficial, intraepithelial, and can be raised and centered in the cornea. The course features periods of activity with symptoms that remit and recur rather than a single acute event.