Which of the following is a spondyloarthropathy commonly associated with anterior uveitis?

• A. Rheumatoid Arthritis
• B. Reactive Arthritis
• C. Gout
• D. Sjögren Syndrome

Answer: (B)

Anterior uveitis is a common eye finding in certain inflammatory rheumatic diseases that are linked by HLA-B27 positivity, a hallmark of spondyloarthropathies. The classic partner to anterior uveitis is reactive arthritis, a spondyloarthropathy characterized by arthritis often with urethritis and conjunctivitis or anterior uveitis. The eye involvement in reactive arthritis tends to be acute and can recur, fitting the pattern seen when this group affects the eye. The other conditions listed are not typically grouped as spondyloarthropathies and don’t have as strong a connection to anterior uveitis: rheumatoid arthritis is primarily a different inflammatory arthritis with a broader spectrum of ocular choices but not the same recurrent anterior uveitis association; gout is a crystal arthropathy with no specific link to anterior uveitis; Sjögren syndrome mainly causes keratoconjunctivitis sicca rather than inflammatory anterior uveitis.