Which statement about Parinaud's Oculoglandular Syndrome is true?

• A. It is bilateral and non-specific
• B. It commonly presents with unilateral granulomatous conjunctivitis and preauricular lymphadenopathy
• C. It is never associated with lymphadenopathy
• D. It is caused by a viral infection

Answer: (B)

Parinaud's oculoglandular syndrome is a granulomatous conjunctivitis that reflects an infection draining to the nearby lymph nodes. The hallmark is a unilateral presentation of granulomatous conjunctivitis on the affected eye, with tender preauricular lymphadenopathy on the same side. This pattern is classically linked to cat scratch disease caused by Bartonella henselae, though other organisms can be involved. Because the condition follows a lymphatic drainage pattern from the eye, the lymph node swelling is typically on the same side as the eye findings. It is not usually bilateral, and it’s not a viral illness, which helps distinguish it from other conjunctivitis presentations.