Which statement is true about the signs associated with thyroid eye disease?

• A. They all involve lid edema as the primary finding
• B. They are unrelated to eyelid position
• C. They are diagnostic markers of glaucoma
• D. They include lid lag and globe-lid movement with gaze

Answer: (B)

Thyroid eye disease produces signs that reflect orbital inflammation and fibrous changes, which affect both eyelid position and how the lids move as the eyes move. A classic feature is lid lag, where the upper lid doesn’t rise with the globe during gaze, and there can be globe-lid movement with gaze, meaning the lid and eye don’t move in perfect sync. These signs are about lid position and dynamic lid movement, not simply eyelid edema, and they are not used as markers for glaucoma. So the true statement is that the signs include lid lag and globe-lid movement with gaze.